Patent · US Active

Processes for the preparation of substituted tetrahydro beta-carbolines

US10947231B2 · kind B2 · utility

0Cited by

15References

6Claims

0Family size

Assignee

PTC THERAPEUTICS, INC. · US

Inventors

Peter Seongwoo Hwang · Edison, US
Young-Choon Moon · Montgomery, US
Arasu Tamil · Edison, US
Hongyan Qi · Plainsboro, US
Neil Gregory Almstead · Princeton, US

Key dates

Filing date	Sep 24, 2019
Grant date	Mar 16, 2021
Priority date	—
Expiry date	Sep 24, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided herein are improved processes for the synthesis of substituted tetrahydro beta-carboline derivatives. In particular, provided herein are improved processes useful for the preparation of (S)-4-chlorophenyl 6-chloro-1-(4-methoxyphenyl)-3,4-dihydro-1H-pyrido[3,4-b]indole-2(9H)-carboxylate. Formula (I):

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.