Method of stabilizing a bioactive peptide against protease hydrolysis
US10947290B2 · kind B2 · utility
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2References
3Claims
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Key dates
| Filing date | Dec 4, 2018 |
| Grant date | Mar 16, 2021 |
| Priority date | — |
| Expiry date | Dec 4, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention includes a thioamide-modified peptide, wherein the thioamide modification increases the in vivo half-life of the peptide. The invention further includes methods of treating or preventing a disease or disorder in a subject in need thereof, the method comprising administering to the subject a thioamide-modified peptide of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.