Exonuclease deficient polymerases
US10947516B2 · kind B2 · utility
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Key dates
| Filing date | Feb 20, 2019 |
| Grant date | Mar 16, 2021 |
| Priority date | — |
| Expiry date | Feb 20, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y207/07007
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Described herein are polymerase variants that are exonuclease deficient. Some variants retain the strand displacement capability comparable to the wild-type or parental polymerase. Some variants have a strand displacement capability that is improved relative to the wild-type or parental polymerase. The variants may have an extension rate that is greater than the wild-type or parental polymerase. The variants may have a waiting time that is less than the wild-type or parental polymerase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.