Patent · US Active

Allele-specific silencing therapy for Dynamin 2-related diseases

US10947540B2 · kind B2 · utility

3Cited by
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13Claims
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Key dates

Filing dateNov 19, 2017
Grant dateMar 16, 2021
Priority date
Expiry dateNov 19, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y306/05005
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases caused by heterozygous mutation and/or overexpression of Dynamin 2.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.