Methods and apparatus for predicting benefit from immunotherapy using tumoral and peritumoral radiomic features
US10950351B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jan 18, 2019 |
| Grant date | Mar 16, 2021 |
| Priority date | — |
| Expiry date | Mar 25, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30061
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Methods, apparatus, and other embodiments predict response to immunotherapy from computed tomography (CT) images of a region of tissue demonstrating non-small cell lung cancer (NSCLC). One example apparatus includes a set of circuits that includes an image acquisition circuit that accesses a CT image of a region of tissue demonstrating cancerous pathology, a tumoral definition circuit that generates a tumoral surface boundary that defines a tumoral volume, a peritumoral segmentation circuit that generates a peritumoral region based on the tumoral surface boundary, and that segments the peritumoral region into a plurality of annular bands, a radiomics circuit that extracts a set of discriminative features from the tumoral volume and at least one of the plurality of annular bands, and a classification circuit that classifies the ROI as a responder or a non-responder, based, at least in part, on the set of discriminative features.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.