Liquid pharmaceutical compositions of baclofen for oral administration

US10952981B2 · kind B2 · utility

Assignee

• Slayback Pharma LLC · US

Inventors

• Sushant Omprakash Dube · Navi Mumbai, IN
• Girish Kumar Jain · Ashti, IN
• Venkateshwar Reddy Keesara · Hyderabad, IN
• Josh Chandy Mathew · Princeton, US
• Purushottam Dattatraya Kulkarni · Deo, IN
• Purushottam Sakhahari Pattewar · Hyderabad, IN
• Balakrishna Reddy Akula · Hyderabad, IN
• Kumarswamy Ummiti · Hyderabad, IN

Key dates

• Filing date: Jan 24, 2020
• Grant date: Mar 23, 2021
• Expiry date: Jan 24, 2040

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/40
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof. More specifically, stable liquid pharmaceutical compositions of baclofen at concentrations of 5 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions are suitable for oral administration, and stable at pH ranges of 5-8 over a variety of storage conditions, including long-term storage for extended periods of time.