Therapeutic window for treatment of ischemia by vagus nerve stimulation
US10953229B1 · kind B1 · utility
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Key dates
| Filing date | Sep 23, 2020 |
| Grant date | Mar 23, 2021 |
| Priority date | — |
| Expiry date | Sep 23, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/36146
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Closed-loop stimulation of the Vagus nerve in response to a detected myocardial ischemia state within a therapeutic window can mitigate or reverse effects of the ischemia. This window is between 0 and 50 seconds of the onset of ischemia, before the myocardial ischemia reaches a statistically significant evolution level. A properly trained machine learning system such as a long short-term memory system can be used to analyze cardiovascular features and detect myocardial ischemia within the therapeutic window.
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