Crystal form of tipifarnib and preparation method and pharmaceutical composition thereof
US10954210B2 · kind B2 · utility
1Cited by
4References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 8, 2016 |
| Grant date | Mar 23, 2021 |
| Priority date | — |
| Expiry date | Dec 8, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel crystal forms of tipifarnib. Compared with the prior art, the crystal forms of tipifarnib have advantages in crystallinity, hygroscopicity, morphology, form stability and chemical stability. The present invention also relates to the preparation methods of crystal forms of tipifarnib, pharmaceutical composition thereof and their use in preparation for treating and/or preventing abnormal cell growth diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.