Antibodies to ticagrelor and methods of use

US10954308B2 · kind B2 · utility

Assignee

• MedImmune Limited · US

Inventors

• Andrew Buchanan · Cambridge, GB
• Sven Nylander · Gately Drive, SE
• Mark Penney · Cambridge, GB
• Philip Newton · Cambridge, GB
• Feenagh Keyes · Cambridge, GB
• Tord Inghardt · Gately Drive, SE

Key dates

• Filing date: Jul 16, 2018
• Grant date: Mar 23, 2021
• Expiry date: Jan 17, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure generally provides antibodies and antigen binding fragments of antibodies that bind ticagrelor and metabolites of ticagrelor. The disclosure also provides compositions comprising the antibodies, nucleic acid molecules encoding the antibodies, methods of treating a patient comprising administering the antibodies, and methods of making and using the antibodies.