Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
US10954500B2 · kind B2 · utility
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Key dates
| Filing date | Oct 21, 2016 |
| Grant date | Mar 23, 2021 |
| Priority date | — |
| Expiry date | Nov 15, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/81
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods to create chemically-induced dimerizing (CID) protein systems and uses thereof are described. The methods utilize antibody binding domain dimerizing proteins. The created systems can be used to regulate cellular events such as gene expression, receptor signaling and cell death to effectuate a variety of clinically relevant treatment outcomes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.