Systems and methods for calibrating and correcting a speckle contrast flowmeter
US10955275B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 18, 2017 |
| Grant date | Mar 23, 2021 |
| Priority date | — |
| Expiry date | Nov 5, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/479
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are systems, methods, and devices for calibrating contrast measurements from laser speckle imaging systems to accurately determine unknown particle motion characteristics, such as flow rate. The calibration stores to memory calibration data, which may include a set of measurements from samples with known particle characteristics and/or estimates of noise, including the effects on contrast arising from undesired signals unrelated to the unknown particle motion characteristics. The calibration data may be accessed and used to correct an empirical measurement of contrast and/or interpolate a value of the unknown particle motion characteristic. The system may include a light source, photodetector, processor, and memory, which can be combined into a single device, such as a wearable device, for providing calibrated flow measurements. The device may be used, for example, to measure blood flow, cardiac output, and heart rate, and can be used to amplify the pulsatile signal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.