Macrocycles, cobalt and iron complexes of same, and methods of making and using same

US10960088B2 · kind B2 · utility

Assignees

• The Research Foundation for The State University of New York · US
• HEALTH RESEARCH, INC. · US

Inventors

• Janet R. Morrow · Williamsville, US
• Pavel Tsitovich · Amherst, US
• Sarina Dorazio · Elba, US
• Abiola Olatunde · Amherst, US
• Joseph Spernyak · West Seneca, US
• Patrick BURNS · Colville, US
• Eric M. SNYDER · Williamsville, US
• Christopher J. Bond · Mercer Island, US

Key dates

• Filing date: Sep 12, 2014
• Grant date: Mar 30, 2021
• Expiry date: Feb 25, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D255/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are macrocyclic compounds and iron or cobalt coordinated macrocyclic compounds. The compounds can be used as MRI contrast agents. Certain compounds are redox active and can be used to assess the biological redox status of a sample.