Patent · US Active

Derivatives and their use as selective inhibitors of caspase-2

US10961219B2 · kind B2 · utility

0Cited by

1References

23Claims

0Family size

Assignees

Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
UNIVERSITÉ PARIS DIDEROT—PARIS 7 · FR

Inventor

Etienne Jacotot · Paris, FR

Key dates

Filing date	Mar 21, 2017
Grant date	Mar 30, 2021
Priority date	—
Expiry date	Mar 21, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a compound of formula (I) wherein P1, P3, P4 and P5 are amino acid residues. The invention also relates to a compound of formula (I) for its use as a Caspase-2 inhibitor and for its therapeutical use. It also concerns the use of a compound of formula (I) as activity base probe to selectively detect Caspase-2 activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.