Patent · US Active

Open-top microfluidic device with structural anchors

US10961496B2 · kind B2 · utility

2Cited by

1References

9Claims

0Family size

Assignee

EMULATE, INC. · US

Inventors

Daniel Levner · Brookline, US
Christopher David Hinojosa · Cambridge, US
Norman Wen · Dedham, US
Antonio Varone · Riverdale, US
Justin Nguyen · Medford, US
Lina Williamson · Chapel Hill, US
S. Jordan Kerns · Reading, US
Catherine Karalis · Brookline, US
Geraldine Hamilton · Cambridge, US
Carol Lucchesi · Westwood, US

Key dates

Filing date	Dec 2, 2016
Grant date	Mar 30, 2021
Priority date	—
Expiry date	Jul 15, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2501/165
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.