Hepatitis B core protein modulators

US10968211B2 · kind B2 · utility

Assignees

• ASSEMBLY BIOSCIENCES, INC. · US
• INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION · US

Inventors

• William W. Turner, Jr. · Bloomington, US
• Lee D. Arnold · Rancho Santa Fe, US
• Hans Maag · Menlo Park, US
• Leping Li · San Francisco, US
• Mark G. Bures · Carmel, US
• Simon Nicolas Haydar · South San Francisco, US
• Samson Francis · Bloomington, US

Key dates

• Filing date: May 30, 2019
• Grant date: Apr 6, 2021
• Expiry date: May 30, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.