Patent · US Active

Methods of processing a fluid including a recombinant therapeutic protein and use thereof

US10968252B2 · kind B2 · utility

0Cited by
5References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 15, 2017
Grant dateApr 6, 2021
Priority date
Expiry dateMay 5, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/31
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

Provided herein are methods of processing a fluid that include the use of one or both of a circuit system including a tangential flow filtration (TFF) unit and a circuit system including a tangential flow virus filtration (TFVF) unit. Also provided are integrated and continuous processes for manufacturing a therapeutic protein drug substance that include a step of processing a fluid including the recombinant therapeutic protein using any of the methods provided herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.