Patent · US Active

Gene signatures for determining ICOS expression

US10968277B2 · kind B2 · utility

0Cited by

17References

21Claims

0Family size

Assignee

Jounce Therapeutics, Inc. · US

Inventors

Jason Reeves · Santa Clara, US
Igor Feldman · Brookline, US
Christopher Harvey · Boston, US
Sriram Sathyanarayanan · Lexington, US
Heather Hirsch · Brookline, US
Lauren Pepper MACKENZIE · Watertown, US
Amit Deshpande · Cambridge, US
Stephen Sazinsky · Melrose, US
Jennifer Michaelson · Cambridge, US
Kutlu Goksu Elpek · Arlington, US

Key dates

Filing date	Oct 21, 2016
Grant date	Apr 6, 2021
Priority date	—
Expiry date	Sep 27, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/158
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Gene expression signatures correlating to ICOS expression levels are provided. Methods of treatment comprising determining ICOS expression levels using gene signatures in patients and administering anti-ICOS antibodies are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.