Patent · US Active

Polymerase variants and uses thereof

US10968438B2 · kind B2 · utility

0Cited by

0References

20Claims

0Family size

Assignee

Roche Sequencing Solutions, Inc. · US

Inventors

Aruna Ayer · Santa Clara, US
Cleoma Arnold · San Jose, US
Charles Wayan Schwab · San Ramon, US
Eileen Thai · San Jose, US
Ilya Lederman · San Francisco, US
Colin Alexander McGaw · Santa Clara, US
Tyler O'Brien Shultz · Santa Clara, US

Key dates

Filing date	Nov 25, 2019
Grant date	Apr 6, 2021
Priority date	—
Expiry date	Nov 25, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y207/07007
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227, I295, Y342, T343, I357, S360, L361, I363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, Q546, A547, L549, I550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624, I628, Y629, R632, N635, M641, A643, I644, T647, I648, T651, I652, K655, W656, D657, V658, H660, F662, L690 and combinations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.