Heart rate variability analysis method, device and use thereof
US10973455B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Aug 4, 2017 |
| Grant date | Apr 13, 2021 |
| Priority date | — |
| Expiry date | Feb 20, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/352
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method and an apparatus for analyzing heart rate Variability (HRV), and use thereof are provided. A low-cost, portable and wearable signal acquisition device is utilized to acquire electrocardiography (ECG) signals of epilepsy patients for 24 hours before treatment, and a time domain index, a frequency domain index and a nonlinear index of the ECG during a long term and during a short term are calculated with a programmed HRV analysis method, and the efficacy of vagus nerve stimulation (VNS) treatment for patients with medically intractable epilepsy is accurately and efficiently predicted based on characteristic parameters for characterizing an effect level of the vagus nerve regulating the heart rate, i.e., vagus nerve activity, thereby avoiding unnecessary costs and avoiding the delay of the optimal treatment timing. In addition, the characteristic parameters obtained by the HRV analysis on the ECG may be utilized to clearly select VNS treatment indication patients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.