System and method for modulating optogenetic vagus nerve in a noninvasive, transcutaneous manner
US10974065B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 31, 2016 |
| Grant date | Apr 13, 2021 |
| Priority date | — |
| Expiry date | Nov 7, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/0663
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A system and method for modulating optogenetic vagus neurons in a noninvasive and transcutaneous manner is disclosed. The system and method comprises a two-dimensional array of organic light emitting diodes (OLEDs), a voltage-generating unit, a control unit, and a feedback loop. The array is placed on a subject's outer ear. Because the array is flexible, it can be closely placed on the skin of the outer ear. The array can deliver optical therapy and monitor heart rate variability (HRV) of the subject simultaneously, and the pixels of the array can be individually addressed. The voltage-generating unit generates pulsed voltage to the OLEDs. The control unit is connected to the array and controls the array and therapeutic patterns. The feedback loop uses the HRV to identify the therapeutic patterns.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.