Inhibitors of meprin α and β

US10975019B2 · kind B2 · utility

Assignee

• Vivoryon Therapeutics AG · DE

Inventors

• Michael Wermann · Halle (Saale), DE
• Mirko Buchholz · Halle (Saale), DE
• Hans-Ulrich Demuth · Halle (Saale), DE
• Daniel Ramsbeck · Halle (Saale), DE
• Dagmar Schlenzig · Bodenwerder, DE
• Stephen Schilling · Bodenwerder, DE

Key dates

• Filing date: Apr 18, 2017
• Grant date: Apr 13, 2021
• Expiry date: Apr 18, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D319/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel hydroxamic acid derivatives as inhibitors of meprin β and/or α, pharmaceutical compositions comprising such compounds, methods for treatment or prophylaxis of diseases or conditions, especially such that are related to meprin β and/or α, and compounds and pharmaceutical compositions for use in such methods.