High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging

US10975060B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Markus Berger · Berlin, DE
• Jessica Lohrke · Berlin, DE
• Christoph-Stephan Hilger · Berlin, DE
• Gregor Jost · Berlin, DE
• Thomas Frenzel · Berlin, DE
• Olaf Panknin · Berlin, DE
• Hubertus Pietsch · Kleinmachnow, DE

Key dates

• Filing date: Nov 24, 2017
• Grant date: Apr 13, 2021
• Expiry date: Nov 24, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D257/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a new class of high relaxivity extracellular gadolinium chelate complexes, to methods of preparing said compounds, and to the use of said compounds as MRI contrast agents.