RIP1 inhibitory compounds and methods for making and using the same
US10975064B2 · kind B2 · utility
14Cited by
5References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 2, 2019 |
| Grant date | Apr 13, 2021 |
| Priority date | — |
| Expiry date | May 2, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/107
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein are kinase inhibitory compounds, such as a receptor-interacting protein-1 (RIP1) kinase inhibitor compounds, as well as pharmaceutical compositions and combinations comprising such inhibitory compounds. The disclosed compounds, pharmaceutical compositions, and/or combinations may be used to inhibit a RIP1 kinase in vivo or ex vivo, and also may treat or prevent a kinase-associated disease or condition, particularly a RIP1-associated disease or condition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.