Patent · US Active

Bis 2′-5′-RR-(3′F-A)(3′F-A) cyclic dinucleotide compound and uses thereof

US10975114B2 · kind B2 · utility

0Cited by

46References

17Claims

0Family size

Assignees

Chinook Therapeutics, Inc. · US
Novartis AG · CH

Inventors

Justin Leong · Union City, US
Chudi Ndubaku · Oakland, US
Jeffrey McKenna · Horsham, GB

Key dates

Filing date	Apr 26, 2018
Grant date	Apr 13, 2021
Priority date	—
Expiry date	Apr 26, 2038

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/585
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides the cyclic dinucleotide compound 2′2′-RR-(3′F-A)(3′F-A) as a highly active immune stimulator that activates DCs via the cytoplasmic receptor known as STING (Stimulator of Interferon Genes), and compositions and uses thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.