Materials and methods for biosynthetic manufacture and utilization of synthetic polypeptides, and products therefrom
US10975363B2 · kind B2 · utility
5Cited by
8References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 1, 2019 |
| Grant date | Apr 13, 2021 |
| Priority date | — |
| Expiry date | Apr 1, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y301/02014
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are novel, synthetic polypeptides having, for example, acyl-acyl carrier protein (ACP) thioesterase (TE) activity, including polypeptides that convert pimeloyl-ACP to pimelic acid. In some aspects, the synthetic polypeptides have advantageous enzymatic activity and/or improved substrate specificity relative to a wild type acyl-ACP TE.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.