Patent · US Active

Methods for purification of messenger RNA

US10975369B2 · kind B2 · utility

2Cited by
5References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 27, 2018
Grant dateApr 13, 2021
Priority date
Expiry dateFeb 27, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y201/03003
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates, in part, to methods for large-scale purification of mRNA. The method includes, at least, a step of centrifuging an mRNA suspension in a centrifuge comprising a porous substrate at a speed sufficient to remove process contaminants and to precipitate purified mRNA composition onto the porous substrate.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.