Site-directed CRISPR/recombinase compositions and methods of integrating transgenes
US10975392B2 · kind B2 · utility
4Cited by
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9Claims
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Key dates
| Filing date | Dec 7, 2015 |
| Grant date | Apr 13, 2021 |
| Priority date | — |
| Expiry date | Dec 7, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/20
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are targeted chimeric polypeptides, compositions thereof, expression vectors, and methods of use thereof, for the generation of transgenic cells, tissues, plants, and animals. The compositions, vectors, and methods of the present invention are also useful in gene therapy and cell therapy techniques. The chimeric polypeptide includes a CRISPR-Cas domain and a recombinase domain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.