Patent · US Active

Genetically modified non-human animal with human or chimeric CD27

US10980222B2 · kind B2 · utility

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12Claims
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Inventors

Key dates

Filing dateJun 7, 2019
Grant dateApr 20, 2021
Priority date
Expiry dateJun 7, 2039

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/70578
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present disclosure relates to genetically modified non-human animals (e.g., genetically-modified mice) that express a human or chimeric (e.g., humanized) CD27. The present disclosure also relates to methods of generating the genetically-modified animals (e.g., genetically modified mice), and methods of using the genetically modified non-human animals (e.g., genetically modified mice) described herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.