Method for transiently disrupting a region of the blood-brain barrier of a human
US10981021B2 · kind B2 · utility
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33Claims
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Key dates
| Filing date | Mar 11, 2016 |
| Grant date | Apr 20, 2021 |
| Priority date | — |
| Expiry date | Aug 10, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2007/0021
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for transiently disrupting a region of the blood-brain barrier (BBB) of a human using ultrasounds in the presence of an ultrasound contrast agent, and uses thereof. The method comprises the application of at least one ultrasound (US) beam with a pressure level higher than 1 MPa and a resonance frequency ranging from 0.5 to 1.5 MHz.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.