Caspase inhibitor and pharmaceutical composition, use and therapeutic method thereof

US10981860B2 · kind B2 · utility

Assignees

• Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · CN
• Medshine Discovery Inc. · CN

Inventors

• Haiying He · Shanghai, CN
• Songliang Wu · Shanghai, CN
• Zhi Luo · Taichung, TW
• Jianfeng Mou · Shanghai, CN
• Fengying Guo · Shanghai, CN
• Chuan Wang · Berkvam Road, US
• Guoqing Li · Montgomery, US
• Minggao Zeng · Shanghai, CN
• Shuhui CHEN · Shanghai, CN

Key dates

• Filing date: May 11, 2017
• Grant date: Apr 20, 2021
• Expiry date: Jul 10, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D451/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.