Spiro compound and use thereof

US10981900B2 · kind B2 · utility

Assignee

• Medshine Discovery Inc. · CN

Inventors

• Peng Zhang · Nanhu, CN
• Lingyun WU · Shanghai, CN
• Jun Yin · Sichuan, CN
• Jian Li · Shanghai, CN
• Shuhui CHEN · Shanghai, CN

Key dates

• Filing date: Feb 28, 2018
• Grant date: Apr 20, 2021
• Expiry date: Feb 28, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure relates to a series of tricyclic compounds and the use thereof as receptor agonists of sphingosine-1-phosphate subtype 1 (S1P1), and in particular relates to compounds as shown in formula (I) or pharmaceutically acceptable salts thereof.