Patent · US Active

Chimeric antigen receptor (CAR) comprising a CD22-binding domain

US10981970B2 · kind B2 · utility

4Cited by

5References

8Claims

0Family size

Assignee

AUTOLUS LIMITED · GB

Inventors

Martin Pulé · London, GB
Shaun Cordoba · London, GB
Shimobi Onuoha · London, GB
Simon Thomas · London, GB

Key dates

Filing date	Jun 29, 2018
Grant date	Apr 20, 2021
Priority date	—
Expiry date	Feb 21, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2510/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a cell which co-expresses a first chimeric antigen receptor (CAR) and second CAR at the cell surface, each CAR comprising an antigen-binding domain, wherein the antigen-binding domain of the first CAR binds to CD19 and the antigen-binding domain of the second CAR binds to CD22.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.