Patent · US Active

Dual receptor antagonistic antigen-binding proteins and uses thereof

US10981999B2 · kind B2 · utility

0Cited by

1References

7Claims

0Family size

Assignee

AMGEN INC. · US

Inventors

Huiquan Han · Thousand Oaks, US
Xiaolan Zhou · Newbury Park, US
Qing Chen · 流花街道, CN
Mei-Mei Tsai · Taipei, TW

Key dates

Filing date	Mar 5, 2019
Grant date	Apr 20, 2021
Priority date	—
Expiry date	Mar 5, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This disclosure related to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.