Patent · US Active

Domain-exchanged antibody

US10982008B2 · kind B2 · utility

0Cited by

1References

12Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Gordana Wozniak-Knopp · Wien, AT
Sylvia Dietrich · Wien, AT
Florian Ruker · Wien, AT
Alec Gross · Newton, US
Stefan Becker · Darmstadt, DE

Key dates

Filing date	Dec 4, 2015
Grant date	Apr 20, 2021
Priority date	—
Expiry date	Dec 4, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention provides for a domain-exchanged antibody comprising a light chain (LC) composed of VL-CH3, and a heavy chain (HC) comprising VH-CH3-CH2-CH3, wherein the VL-CH3 of the LC is dimerising with the VH-CH3 of the HC thereby forming a domain-exchanged LC/HC dimer comprising a CH3LC/CH3HC domain pair, and means and method for producing the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.