Patent · US Active

Modified factor IX polypeptides and uses thereof

US10982203B2 · kind B2 · utility

0Cited by

39References

42Claims

0Family size

Assignee

Catalyst Biosciences, Inc. · US

Inventors

Edwin L. Madison · Dallas, US
Christopher D. Thanos · Tiburon, US
Grant E. BLOUSE · Burlingame, US

Key dates

Filing date	Mar 29, 2016
Grant date	Apr 20, 2021
Priority date	—
Expiry date	Mar 30, 2037

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K48/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Nucleic acid molecules encoding modified factor IX (FIX) polypeptides and uses thereof are provided. Such modified FIX polypeptides include FIXa and other forms of FIX. Among the modified FIX polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.