Method for producing meso-galactaric acid by contacting a fungal cell with a biomaterial having galacturonic acid
US10982239B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | May 19, 2017 |
| Grant date | Apr 20, 2021 |
| Priority date | — |
| Expiry date | May 19, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y501/02002
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a field of genetically modified fungal cells and converting galacturonic acid to meso-galactaric acid, more precisely to a method of producing meso-galactaric acid. The invention further relates to recombinant fungal cells having a specific combination of modifications including but not limited to expression of uronate dehydrogenase enzyme, reduced D-galacturonic acid reductase activity, and furthermore reduced meso-galactaric acid catabolism, as well as uses and methods related thereto.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.