DNA polymerase mutants having enhanced template discrimination activity
US10982247B2 · kind B2 · utility
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Key dates
| Filing date | Dec 21, 2016 |
| Grant date | Apr 20, 2021 |
| Priority date | — |
| Expiry date | Dec 21, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y207/07007
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to mutant DNA polymerases having an enhanced template discrimination activity compared with the corresponding unmodified DNA polymerase counterparts, wherein the amino acid sequence of the mutant DNA polymerase includes at least one substitution at residue positions structurally and functionally homologous or orthologous positions 783 or 784 of an unmodified Taq DNA polymerase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.