Methods of sequencing, determining, pairing, and validating therapeutic agents and disease specific antigens
US10982258B2 · kind B2 · utility
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37Claims
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Key dates
| Filing date | Apr 27, 2016 |
| Grant date | Apr 20, 2021 |
| Priority date | — |
| Expiry date | Aug 15, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2563/185
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are methods and composition for immune repertoire sequencing and single cell barcoding. The methods and compositions can be used to pair any two sequences originating from a single cell, such as heavy and light chain antibody sequences, for antibody discovery, disease and immune diagnostics, and low error sequencing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.