Patent · US Active

DNA origami nanostructures for treatment of acute kidney injury

US10987373B2 · kind B2 · utility

1Cited by
7References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 8, 2018
Grant dateApr 27, 2021
Priority date
Expiry dateApr 15, 2038

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/347
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed herein are methods of treating acute kidney injury. The A method can include administering a sufficient amount of a DNA origami nanostructure to a subject afflicted with AKI to increase an excretory function of said subject. In some examples, the DNA origami nanostructure includes a scaffold strand and a plurality of staple strands, in which the scaffold strand comprises a M1 3 viral genome having a length of 7249 base pairs; and each staple strand of the plurality of staple strands has a length of about 20 to 60 base pairs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.