Substituted pyrazole-pyrimidines, variants thereof, and uses therefore
US10988460B2 · kind B2 · utility
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Key dates
| Filing date | Dec 11, 2017 |
| Grant date | Apr 27, 2021 |
| Priority date | — |
| Expiry date | Dec 11, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are substituted pyrazole-pyrimidine compounds of Formula (I) and variants thereof for the treatment, for example, of diseases associated with P2X purinergic receptors. In one embodiment, the P2X3 and/or P2X2/3 antagonists disclosed herein are potentially useful, for example, for the treatment of visceral organ, cardiovascular and pain-related diseases, conditions and disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.