Hydroxytyrosol ursolic acid ester with antioxidant activity and methods of preparing the same

US10995053B1 · kind B1 · utility

Assignee

• SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY · CN

Inventors

• Han Li · Xi'an, CN
• Nan Hui · Xi'an, CN
• Bin Tian · Xi'an, CN
• Xingke Ju · Xi'an, CN
• Yuzhi Liu · Xi'an, CN
• Dan Yang · Wuxi, CN
• Jingwen Xu · Xi'an, CN
• Liang Qi · Xi'an, CN
• Qianqian Zhao · Xi'an, CN
• Yongbo Wang · Xi'an, CN

Key dates

• Filing date: Mar 20, 2020
• Grant date: May 4, 2021
• Expiry date: Mar 20, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/52
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

A compound having the formula (I): is disclosed. Methods of preparing the compound of formula (I) are also disclosed. The compound of formula (I) can be prepared by reacting a compound of formula (II) with a compound of formula (III) in an organic solvent with EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide). The compound of formula (I) can also be prepared by reacting the compound of formula (II) with the compound of formula (III) in 1-ethyl-3-methylimidazolium hexafluorophosphate as a solvent with silicomolybdic acid as a catalyst.