Patent · US Active

Libraries of modified fibronectin type III tenth domain-containing polypeptides

US10995131B2 · kind B2 · utility

1Cited by

68References

14Claims

0Family size

Assignee

Bristol-Myers Squibb Company · US

Inventors

Yan Chen · Foster City, US
Elena Getmanova · Lexington, US
Martin C. Wright · Belmont, US
Alan S. Harris · Andover, US
Ai Ching Lim · Redwood City, US
Jochem Gokemeijer · Wayland, US
Lin Sun · Dedham, US
Michael Wittekind · Bainbridge Island, US

Key dates

Filing date	Nov 29, 2017
Grant date	May 4, 2021
Priority date	—
Expiry date	Nov 29, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/43
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.