Patent · US Active

Rapid antibiotic susceptibility test using membrane fluorescence staining and spectral intensity ratio improved by flow cytometry dead to live population ratio

US10995358B2 · kind B2 · utility

0Cited by

5References

20Claims

0Family size

Assignee

POCARED Diagnostics LTD. · IL

Inventors

Moshe Ben-David · Nes Ziona, IL
Eran Zahavy · Rehovot, IL
Gal Ingber · Rekhasim, IL

Key dates

Filing date	Jul 12, 2018
Grant date	May 4, 2021
Priority date	—
Expiry date	Dec 15, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/06
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration (MIC)), thereby providing a means for rapid Antibiotic Susceptibility Testing (AST). This allows for a quick and easy means for clinicians to determine a suitable treatment regimen for patients suffering from bacterial infections and those that eventually lead to sepsis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.