Devices and systems with fluidic nanofunnels for processing single molecules

US10996212B2 · kind B2 · utility

Assignee

• The University of North Carolina at Chapel Hill · US

Inventors

• John Michael Ramsey · Chapel Hill, US
• Laurent Menard · Palaiseau, FR
• Jinsheng Zhou · Hamilton, CA
• Michael Rubinstein · Natick, US
• Sergey Panyukov · Moscow, RU

Key dates

• Filing date: May 2, 2018
• Grant date: May 4, 2021
• Expiry date: Sep 1, 2039

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/0421
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods of forming a chip with fluidic channels include forming (e.g., milling) at least one nanofunnel with a wide end and a narrow end into a planar substrate, the nanofunnel having a length, with width and depth dimensions that both vary over its length and forming (e.g., milling) at least one nanochannel into the planar substrate at an interface adjacent the narrow end of the nanofunnel.