Pre-coated surfaces for imaging biomolecules
US10996227B2 · kind B2 · utility
0Cited by
0References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 9, 2016 |
| Grant date | May 4, 2021 |
| Priority date | — |
| Expiry date | Mar 19, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/948
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Pre-coated analysis substrates, and methods of making the substrates and using them to analyze animal tissue, are described. The pre-coated analysis substrates can be made by forming a matrix surface on an analysis substrate; adding a protease to the matrix surface to form a pre-coated analysis substrate; and placing an animal tissue specimen on the matrix surface. The animal tissue can then be analyzed by allowing the protease to partially digest the animal tissue specimen; and analyzing the partially digested animal tissue specimen by mass spectrometry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.