System and method for electrophoretic decellularization
US11000031B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 12, 2018 |
| Grant date | May 11, 2021 |
| Priority date | — |
| Expiry date | May 12, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N1/066
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of decellularizing a tissue includes disposing the tissue within a device, the device. The device includes a container, first and second electrodes disposed within the container and defining a space between the first and second electrodes to receive the tissue, a perfusion pump, and a conduit connected to the perfusion pump to transport a decellularization composition from the pump into the tissue. The method further includes disposing the decellularization composition within the container to surround the tissue and contact the first and second electrodes, applying an electric potential across the first and second electrodes, and perfusing the decullarization composition into the tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.