P53 degradation inducing molecule and pharmaceutical composition
US11007269B2 · kind B2 · utility
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2References
9Claims
0Family size
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Key dates
| Filing date | Nov 13, 2017 |
| Grant date | May 18, 2021 |
| Priority date | — |
| Expiry date | Feb 15, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0808
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A p53 degradation inducing molecule which can induce degradation of p53 proteins or p53 composites, and a pharmaceutical composition containing said p53 degradation inducing molecule are provided. This p53 degradation inducing molecule is a conjugate of a p53 affinity molecule which has affinity for p53 proteins or p53 composites, and a proteolysis induction tag which has affinity for protease and which does not inhibit proteolysis of proteins by protease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.