Patent · US Active

Designer osteogenic proteins

US11008373B2 · kind B2 · utility

0Cited by

13References

8Claims

0Family size

Assignee

Wyeth, LLC · US

Inventors

Stephen Berasi · Arlington, US
Robert Vincent Martinez · Carlisle, US
Michael John Cain · Exeter, US
John M. Wozney · Hudson, US
Howard Seeherman · Cambridge, US
Zong Sean Juo · Cambridge, US
Valerie Calabro · Ponteau, FR
Christopher BROWN · Chelmsford, US

Key dates

Filing date	Dec 6, 2018
Grant date	May 18, 2021
Priority date	—
Expiry date	Dec 15, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N5/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.