Methods of treating a fibrotic disorder by administering transforming growth factor beta receptor II fusion polypeptides
US11008377B2 · kind B2 · utility
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27References
16Claims
0Family size
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Key dates
| Filing date | Jan 30, 2020 |
| Grant date | May 18, 2021 |
| Priority date | — |
| Expiry date | Feb 1, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In certain aspects, the present disclosure relates to polypeptides comprising a truncated, ligand-binding portion of the extracellular domain of TβRII polypeptide useful to selectively antagonize a TβRII ligand. The disclosure further provides compositions and methods for use in treating or preventing TGFβ associated disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.