Patent · US Active

Polypeptides

US11008396B2 · kind B2 · utility

2Cited by

1References

10Claims

0Family size

Assignee

ALLIGATOR BIOSCIENCE AB · SE

Inventors

Peter Ellmark · Lund, SE
Christina Furebring · Lund, SE
Per Norlen · Lund, SE
Eva Dahlen · Lund, SE
Sara Fritzell · Lund, SE
Niina Veitonmaki · Lund, SE
Laura Von Schantz · Lund, SE

Key dates

Filing date	May 20, 2016
Grant date	May 18, 2021
Priority date	—
Expiry date	May 11, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/74
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides bispecific polypeptides, such as bispecific antibodies, comprising a first binding domain capable of specifically binding to a first T cell target, and a second binding domain capable of specifically binding to a second T cell target, wherein the first and second T cell targets are different targets. The invention further provides compositions of said bispecific polypeptides, as well as methods and uses of the same. The first and/or second T cell target may be selected from the group consisting of OX40, CTLA-4, CD137, CD27, GITR and CD28.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.